Reactome | Serine metabolism

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Serine metabolism Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11050122
displayName	Serine metabolism
eventOf	[Pathway:R-DDI-71291] Metabolism of amino acids and derivatives - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2588486] alpha-amino acid metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-DDI-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Dictyostelium discoideum [Reaction:R-DDI-977324] PSPH:Mg2+ dimer dephosphorylates O-P-Ser - Dictyostelium discoideum [Reaction:R-DDI-8932980] SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane - Dictyostelium discoideum [Reaction:R-DDI-9929460] SDS dimers:PXLP convert L-Ser to PYR and NH4+ - Dictyostelium discoideum [Reaction:R-DDI-9034539] PXLP-K56-SRR dimer deaminates L-Ser - Dictyostelium discoideum [Reaction:R-DDI-9014766] PXLP-K56-SRR dimer isomerises L-Ser to D-Ser - Dictyostelium discoideum [Reaction:R-DDI-9014741] PXLP-K56-SRR dimer deaminates D-Ser - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-977347] Serine metabolism - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Serine metabolism
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-977347
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-71291] Metabolism of amino acids and derivatives
(hasEncapsulatedEvent)	[Pathway:R-DDI-9856872] Malate-aspartate shuttle
(inferredTo)	[Pathway:R-HSA-977347] Serine metabolism