Reactome | ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells

Schema > Reaction > Entries

ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells Show undefined attributes

catalystActivity	[CatalystActivity:11046062] ABC-type transporter activity of ABCC2, ABCC3 [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11046064
displayName	ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells
eventOf	[Pathway:R-DDI-9749641] Aspirin ADME - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9750656] ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [DefinedSet:R-ALL-9750692] salicylate metabolites [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells ABCC2, ABCC3 transport salicylate metabolites out of hepatic cells
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] [DefinedSet:R-ALL-9750678] salicylate metabolites [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-9750656
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-9749641] Aspirin ADME
(inferredTo)	[Reaction:R-HSA-9750656] ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells

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