Reactome | Vanin hydrolyses pantetheine to PanK, 2AET

Schema > Reaction > Entries

Vanin hydrolyses pantetheine to PanK, 2AET Show undefined attributes

catalystActivity	[CatalystActivity:11040933] pantetheine hydrolase activity of VNN1,VNN2 [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11040935
displayName	Vanin hydrolyses pantetheine to PanK, 2AET
eventOf	[Pathway:R-DDI-199220] Vitamin B5 (pantothenate) metabolism - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8938300] Vanin hydrolyses pantetheine to PanK, 2AET - Homo sapiens
input	[SimpleEntity:R-ALL-8939157] Pantetheine [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Vanin hydrolyses pantetheine to PanK, 2AET (R)-pantetheine + H2O => (R)-pantothenate + cysteamine
output	[SimpleEntity:R-ALL-9837424] 2AET [extracellular region] [SimpleEntity:R-ALL-199192] PanK [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-8938300
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-199220] Vitamin B5 (pantothenate) metabolism
(inferredTo)	[Reaction:R-HSA-8938300] Vanin hydrolyses pantetheine to PanK, 2AET

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