Reactome | DNA Damage Bypass

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11049266
displayName	DNA Damage Bypass
eventOf	[TopLevelPathway:R-DDI-73894] DNA Repair - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:15669] translesion synthesis
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DDI-110313] Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-73893] DNA Damage Bypass - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	DNA Damage Bypass
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-73893
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[TopLevelPathway:R-DDI-73894] DNA Repair
(inferredTo)	[Pathway:R-HSA-73893] DNA Damage Bypass

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