Reactome | Pyrimidine salvage

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Pyrimidine salvage Show undefined attributes

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11049064
displayName	Pyrimidine salvage
eventOf	[Pathway:R-DDI-8956321] Nucleotide salvage - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:160588] pyrimidine nucleoside salvage
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DDI-109759] deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] - Dictyostelium discoideum [Reaction:R-DDI-74372] uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] - Dictyostelium discoideum [Reaction:R-DDI-73632] phosphorylation of 2'-Deoxythymidine to dTMP - Dictyostelium discoideum [Reaction:R-DDI-8954327] UCKL1 phosphorylates urindine, cytidine - Dictyostelium discoideum [Reaction:R-DDI-73599] cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] - Dictyostelium discoideum [Reaction:R-DDI-109903] cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] - Dictyostelium discoideum [Reaction:R-DDI-73598] (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) - Dictyostelium discoideum [Reaction:R-DDI-73608] deamination of 2'-Deoxycytidine to 2'-Deoxyuridine - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-73614] Pyrimidine salvage - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Pyrimidine salvage
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-73614
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-8956321] Nucleotide salvage
(inferredTo)	[Pathway:R-HSA-73614] Pyrimidine salvage

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