Reactome | AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters

Schema > Reaction > Entries

AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters Show undefined attributes

catalystActivity	[CatalystActivity:11030379] long-chain-alcohol O-fatty-acyltransferase activity of AWAT1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11030381
displayName	AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters
eventOf	[Pathway:R-DDI-2142753] Arachidonate metabolism - Dictyostelium discoideum [Pathway:R-DDI-9640463] Wax biosynthesis - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5696424] AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters - Homo sapiens
input	[SimpleEntity:R-ALL-192172] Acyl-CoA [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-5696426] ARACOH [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters
output	[SimpleEntity:R-ALL-5696412] arachidyl ester [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-162743] CoA-SH [endoplasmic reticulum lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-5696424
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-9640463] Wax biosynthesis [Pathway:R-DDI-2142753] Arachidonate metabolism
(inferredTo)	[Reaction:R-HSA-5696424] AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters

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