Reactome | BRCA1:BARD1 [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:11045649] ubiquitin-protein transferase activity of BRCA1:BARD1 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DDI-9701007] BRCA1:BARD1:BAP1 [nucleoplasm] - Dictyostelium discoideum
consumedByEvent	[Reaction:R-DDI-9701000] BRCA1:BARD1 heterodimer autoubiquitinates - Dictyostelium discoideum [Reaction:R-DDI-9701003] BAP1 binds BRCA1:BARD1 heterodimer - Dictyostelium discoideum
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11025389
displayName	BRCA1:BARD1 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-DDI-5659775] BARD1 [nucleoplasm] [EntityWithAccessionedSequence:R-DDI-50949] BRCA1 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5659802] BRCA1:BARD1 [nucleoplasm] - Homo sapiens
maxDepth	2
name	BRCA1:BARD1
producedByEvent	[Reaction:R-DDI-5659781] BRCA1 forms a heterodimer with BARD1 - Dictyostelium discoideum
schemaClass	Complex
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-5659802
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DDI-9701003] BAP1 binds BRCA1:BARD1 heterodimer [Reaction:R-DDI-9701000] BRCA1:BARD1 heterodimer autoubiquitinates
(hasComponent)	[Complex:R-DDI-9701007] BRCA1:BARD1:BAP1 [nucleoplasm]
(physicalEntity)	[CatalystActivity:11045649] ubiquitin-protein transferase activity of BRCA1:BARD1 [nucleoplasm]
(output)	[Reaction:R-DDI-5659781] BRCA1 forms a heterodimer with BARD1
(inferredTo)	[Complex:R-HSA-5659802] BRCA1:BARD1 [nucleoplasm]