Reactome | Cell-extracellular matrix interactions

Schema > Pathway > Entries

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11049986
displayName	Cell-extracellular matrix interactions
eventOf	[Pathway:R-DDI-446728] Cell junction organization - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-DDI-446388] Regulation of cytoskeletal remodeling and cell spreading by IPP complex components - Dictyostelium discoideum [Reaction:R-DDI-446364] Migfilin interacts with VASP - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-446353] Cell-extracellular matrix interactions - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Cell-extracellular matrix interactions
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-446353
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-446728] Cell junction organization
(inferredTo)	[Pathway:R-HSA-446353] Cell-extracellular matrix interactions

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