Reactome | Peroxisomal uptake of very long-chain fatty acyl CoA

Schema > Reaction > Entries

Peroxisomal uptake of very long-chain fatty acyl CoA Show undefined attributes

catalystActivity	[CatalystActivity:11009704] ATPase-coupled transmembrane transporter activity of ABCD1 homodimer [peroxisomal membrane]
category	transition
compartment	[Compartment:17947] peroxisomal membrane
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11009706
displayName	Peroxisomal uptake of very long-chain fatty acyl CoA
eventOf	[Pathway:R-DDI-390247] Beta-oxidation of very long chain fatty acids - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-390393] Peroxisomal uptake of very long-chain fatty acyl CoA - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] 2 × [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-5695971] VLCFA-CoA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Peroxisomal uptake of very long-chain fatty acyl CoA a very long-chain fatty acyl-CoA(out) + ATP + 2 H2O => a very long-chain fatty acid(in) + ADP + CoA + 2 H(+)
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol] 2 × [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-9914044] VLCFA [peroxisomal matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-390393
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-390247] Beta-oxidation of very long chain fatty acids
(inferredTo)	[Reaction:R-HSA-390393] Peroxisomal uptake of very long-chain fatty acyl CoA

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