Reactome | Signaling by GPCR

Schema > Pathway > Entries

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11049286
displayName	Signaling by GPCR
eventOf	[TopLevelPathway:R-DDI-162582] Signal Transduction - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-DDI-500792] GPCR ligand binding - Dictyostelium discoideum [Pathway:R-DDI-388396] GPCR downstream signalling - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-372790] Signaling by GPCR - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	12
name	Signaling by GPCR
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-372790
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[TopLevelPathway:R-DDI-162582] Signal Transduction
(inferredTo)	[Pathway:R-HSA-372790] Signaling by GPCR

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