Reactome | Deacetylation of cohesin

Schema > Reaction > Entries

Deacetylation of cohesin Show undefined attributes

catalystActivity	[CatalystActivity:11020219] histone deacetylase activity of HDAC8 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11020221
displayName	Deacetylation of cohesin
eventOf	[Pathway:R-DDI-2500257] Resolution of Sister Chromatid Cohesion - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2545253] Deacetylation of cohesin - Homo sapiens
input	2 × [SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [Complex:R-DDI-2484812] p-Ac-Cohesin:PDS5:WAPAL [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Deacetylation of cohesin
output	2 × [SimpleEntity:R-ALL-76183] Ac-CoA [cytosol] [Complex:R-DDI-2545249] p-Cohesin:PDS5:WAPAL [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-2545253
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-2500257] Resolution of Sister Chromatid Cohesion
(inferredTo)	[Reaction:R-HSA-2545253] Deacetylation of cohesin

Cite Us!