Reactome | Fibulin-1 and -2 bind fibronectin

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11020192
displayName	Fibulin-1 and -2 bind fibronectin
eventOf	[Pathway:R-DDI-2129379] Molecules associated with elastic fibres - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2537665] Fibulin-1 and -2 bind fibronectin - Homo sapiens
input	[Polymer:R-DDI-2327729] Fibronectin matrix [extracellular region] [DefinedSet:R-DDI-2161298-3] Homologues of FBLN2 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Fibulin-1 and -2 bind fibronectin FBLN1, FBLN2 bind fibronectin
output	[Complex:R-DDI-2537655] FBLN1, FBLN2:Fibronectin matrix [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-2537665
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-2129379] Molecules associated with elastic fibres
(inferredTo)	[Reaction:R-HSA-2537665] Fibulin-1 and -2 bind fibronectin

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