Reactome | Synthesis of Hepoxilins (HX) and Trioxilins (TrX)

Schema > Pathway > Entries

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11050284
displayName	Synthesis of Hepoxilins (HX) and Trioxilins (TrX)
eventOf	[Pathway:R-DDI-2142753] Arachidonate metabolism - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:9956] arachidonate metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-DDI-2161794] Arachidonate is converted to HXA3/B3 by ALOX12 - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-2142696] Synthesis of Hepoxilins (HX) and Trioxilins (TrX) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Synthesis of Hepoxilins (HX) and Trioxilins (TrX)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-2142696
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-2142753] Arachidonate metabolism
(inferredTo)	[Pathway:R-HSA-2142696] Synthesis of Hepoxilins (HX) and Trioxilins (TrX)

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