Reactome | Thyroxine biosynthesis

Schema > Pathway > Entries

created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11049760
displayName	Thyroxine biosynthesis
eventOf	[Pathway:R-DDI-209776] Metabolism of amine-derived hormones - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:19403] thyroid hormone generation
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-DDI-350864] Regulation of thyroid hormone activity - Dictyostelium discoideum
inferredFrom	[Pathway:R-HSA-209968] Thyroxine biosynthesis - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Thyroxine biosynthesis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-209968
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-209776] Metabolism of amine-derived hormones
(inferredTo)	[Pathway:R-HSA-209968] Thyroxine biosynthesis

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