Reactome | ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2

Schema > Reaction > Entries

ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 Show undefined attributes

catalystActivity	[CatalystActivity:11004152] electron-transferring-flavoprotein dehydrogenase activity of ETFDH [mitochondrial inner membrane]
category	transition
compartment	[Compartment:5460] mitochondrial matrix [Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11004154
displayName	ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2
eventOf	[Pathway:R-DDI-611105] Respiratory electron transport - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DDI-164651] Electron transfer from ubiquinol to cytochrome c of complex III - Dictyostelium discoideum [Reaction:R-DDI-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF - Dictyostelium discoideum
inferredFrom	[Reaction:R-HSA-169270] ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 - Homo sapiens
input	[SimpleEntity:R-ALL-73663] CoQ [mitochondrial inner membrane] [Complex:R-DDI-169268] ETF:FADH2 [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 Transfer of electrons from ETF to ubiquinone by ETF-QO
output	[SimpleEntity:R-ALL-2162198] CoQH2 [mitochondrial inner membrane] [Complex:R-DDI-169267] ETF:FAD [mitochondrial matrix] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix]
precedingEvent	[Reaction:R-DDI-164651] Electron transfer from ubiquinol to cytochrome c of complex III - Dictyostelium discoideum [Reaction:R-DDI-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF - Dictyostelium discoideum
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-169270
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-611105] Respiratory electron transport
(precedingEvent)	[Reaction:R-DDI-164651] Electron transfer from ubiquinol to cytochrome c of complex III [Reaction:R-DDI-169260] Reducing equivalents from beta-oxidation of fatty acids transfer to ETF
(inferredTo)	[Reaction:R-HSA-169270] ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2

Cite Us!