Reactome | MDP elicits a NOD2 response

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11004010
displayName	MDP elicits a NOD2 response
eventOf	[Pathway:R-DDI-168638] NOD1/2 Signaling Pathway - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DDI-708349] Activated NOD2 oligomerizes - Dictyostelium discoideum
inferredFrom	[Reaction:R-HSA-168412] MDP elicits a NOD2 response - Homo sapiens
input	[DefinedSet:R-DDI-168411-5] Homologues of NOD2 [cytosol] [SimpleEntity:R-ALL-708341] MDP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MDP elicits a NOD2 response
output	[Complex:R-DDI-168414] MDP:NOD2 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-168412
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DDI-168638] NOD1/2 Signaling Pathway
(precedingEvent)	[Reaction:R-DDI-708349] Activated NOD2 oligomerizes
(inferredTo)	[Reaction:R-HSA-168412] MDP elicits a NOD2 response

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