Reactome | RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DDI-1363300] RBL2:E2F4/5:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] - Dictyostelium discoideum [Complex:R-DDI-1227666] HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] - Dictyostelium discoideum
consumedByEvent	[Reaction:R-DDI-1363303] p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 - Dictyostelium discoideum [Reaction:R-DDI-1226094] Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex - Dictyostelium discoideum [Reaction:R-DDI-1227670] Recruitment of HDAC1 by p130 (RBL2) - Dictyostelium discoideum
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11015800
displayName	RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-DDI-68664] E2F [nucleoplasm] [EntityWithAccessionedSequence:R-DDI-389102] rblA [nucleoplasm] [EntityWithAccessionedSequence:R-DDI-68652] tfdp2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-1226089] RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] - Homo sapiens [Complex:R-HSA-6798265] E2F4:(TFDP1,TFDP2):(RBL1,RBL2) [nucleoplasm] - Homo sapiens
maxDepth	2
name	RBL2:E2F4,E2F5:TFDP1,TFDP2
schemaClass	Complex
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-1226089
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DDI-1363303] p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 [Reaction:R-DDI-1227670] Recruitment of HDAC1 by p130 (RBL2) [Reaction:R-DDI-1226094] Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex
(hasComponent)	[Complex:R-DDI-1363300] RBL2:E2F4/5:DP1/2:Cyclin E/A:CDK2 [nucleoplasm] [Complex:R-DDI-1227666] HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] [Complex:R-DDI-1362264] DREAM complex [nucleoplasm]
(inferredTo)	[Complex:R-HSA-1226089] RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] [Complex:R-HSA-6798265] E2F4:(TFDP1,TFDP2):(RBL1,RBL2) [nucleoplasm]

Cite Us!