Reactome | Formation of DSIF complex

Schema > Reaction > Entries

Formation of DSIF complex Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
dbId	11002694
displayName	Formation of DSIF complex
eventOf	[Pathway:R-DDI-674695] RNA Polymerase II Pre-transcription Events - Dictyostelium discoideum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DDI-113407] DSIF complex binds to RNA Pol II (hypophosphorylated) - Dictyostelium discoideum
inferredFrom	[Reaction:R-HSA-112434] Formation of DSIF complex - Homo sapiens
input	[EntityWithAccessionedSequence:R-DDI-3009372] phospho-spt5 [nucleoplasm] [EntityWithAccessionedSequence:R-DDI-64905] spt4 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Formation of DSIF complex
output	[Complex:R-DDI-112420] DSIF complex [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170941] Dictyostelium discoideum
stId	R-DDI-112434
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DDI-674695] RNA Polymerase II Pre-transcription Events
(precedingEvent)	[Reaction:R-DDI-113407] DSIF complex binds to RNA Pol II (hypophosphorylated)
(inferredTo)	[Reaction:R-HSA-112434] Formation of DSIF complex