Reactome | CHD8 binds WDR5

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10327943
displayName	CHD8 binds WDR5
eventOf	[Pathway:R-CFA-9943962] CHD6, CHD7, CHD8, CHD9 subfamily - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9944456] CHD8 binds WDR5 - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-3221598] CHD8 [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-1629838] WDR5 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	CHD8 binds WDR5
output	[Complex:R-CFA-9944446] CHD8:WDR5 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9944456
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-9943962] CHD6, CHD7, CHD8, CHD9 subfamily
(inferredTo)	[Reaction:R-HSA-9944456] CHD8 binds WDR5