Reactome | FXI + kininogen -> FXI:kininogen

Schema > Reaction > Entries

FXI + kininogen -> FXI:kininogen Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10327521
displayName	FXI + kininogen -> FXI:kininogen
eventOf	[Pathway:R-CFA-9935598] FXIIa, PKa-dependent activation of coagulation pathway - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9936440] FXI + kininogen -> FXI:kininogen - Homo sapiens
input	[Complex:R-CFA-158234] factor XI [extracellular region] [EntityWithAccessionedSequence:R-CFA-158125] KNG1 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	FXI + kininogen -> FXI:kininogen KLKB1(20-638) + KNG1(19-644) -> KLKB1(20-638):KNG1(19-644)
output	[Complex:R-CFA-9936459] factor XI:kininogen [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9936440
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9935598] FXIIa, PKa-dependent activation of coagulation pathway
(inferredTo)	[Reaction:R-HSA-9936440] FXI + kininogen -> FXI:kininogen

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