Reactome | The NEXT complex and ZC3H18 bind CBCA:m7GpppN-RNA

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The NEXT complex and ZC3H18 bind CBCA:m7GpppN-RNA Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10326844
displayName	The NEXT complex and ZC3H18 bind CBCA:m7GpppN-RNA
eventOf	[Pathway:R-CFA-9930044] Nuclear RNA decay - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-9934522] NEXT:ZC3H18:CBCA:m7GpppN-RNA binds the RNA exosome - Canis familiaris
inferredFrom	[Reaction:R-HSA-9930056] The NEXT complex and ZC3H18 bind CBCA:m7GpppN-RNA - Homo sapiens
input	[Complex:R-CFA-9930058] CBCA:m7GpppN-RNA [nucleoplasm] [Complex:R-CFA-9935998] NEXT homodimer [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-9930040] ZC3H18 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	The NEXT complex and ZC3H18 bind CBCA:m7GpppN-RNA
output	[Complex:R-CFA-9930062] NEXT:ZC3H18:CBCA:m7GpppN-RNA [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9930056
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9930044] Nuclear RNA decay
(precedingEvent)	[Reaction:R-CFA-9934522] NEXT:ZC3H18:CBCA:m7GpppN-RNA binds the RNA exosome
(inferredTo)	[Reaction:R-HSA-9930056] The NEXT complex and ZC3H18 bind CBCA:m7GpppN-RNA

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