Reactome | Antigen processing: Ub, ATP-independent proteasomal degradation

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Antigen processing: Ub, ATP-independent proteasomal degradation Show undefined attributes

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10331995
displayName	Antigen processing: Ub, ATP-independent proteasomal degradation
eventOf	[Pathway:R-CFA-983169] Class I MHC mediated antigen processing & presentation - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:260545] proteasomal ubiquitin-independent protein catabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[BlackBoxEvent:R-CFA-9912655] Proteasomal cleavage of intracellular substrate (immunoproteasome catalyst) - Canis familiaris [BlackBoxEvent:R-CFA-9912636] Proteasomal cleavage of intracellular substrate (PA28-alpha-beta-20S proteasome catalyst) - Canis familiaris
inferredFrom	[Pathway:R-HSA-9912633] Antigen processing: Ub, ATP-independent proteasomal degradation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Antigen processing: Ub, ATP-independent proteasomal degradation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-9912633
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-983169] Class I MHC mediated antigen processing & presentation
(inferredTo)	[Pathway:R-HSA-9912633] Antigen processing: Ub, ATP-independent proteasomal degradation

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