Reactome | TGFBR3 phosphorylation by TGFBR2 complex

Schema > Reaction > Entries

TGFBR3 phosphorylation by TGFBR2 complex Show undefined attributes

catalystActivity	[CatalystActivity:10324555] protein serine/threonine kinase activity of TGFBR2 dimer:TGFB1 dimer:TGFBR1 dimer [plasma membrane]
category	transition
compartment	[Compartment:947587] cytoplasmic side of plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10324557
displayName	TGFBR3 phosphorylation by TGFBR2 complex
eventOf	[Pathway:R-CFA-9839389] TGFBR3 regulates TGF-beta signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-9839378] TGFBR3 binding to ARRB1/2 - Canis familiaris
inferredFrom	[Reaction:R-HSA-9839363] TGFBR3 phosphorylation by TGFBR2 complex - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-CFA-9839341] TGFB1,TGFB2:TGFBR3:TGFBR2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	TGFBR3 phosphorylation by TGFBR2 complex
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-CFA-9839395] TGFB1,TGFB2:pTGFBR3:TGFBR2 [plasma membrane]
precedingEvent	[Reaction:R-CFA-9839390] TGFBR3 complex binds to TGFBR2 - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9839363
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9839389] TGFBR3 regulates TGF-beta signaling
(precedingEvent)	[Reaction:R-CFA-9839378] TGFBR3 binding to ARRB1/2
(inferredTo)	[Reaction:R-HSA-9839363] TGFBR3 phosphorylation by TGFBR2 complex

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