Reactome | Binding of newly synthesized MHC class I heavy chain (HC) with calnexin

Schema > Reaction > Entries

Binding of newly synthesized MHC class I heavy chain (HC) with calnexin Show undefined attributes

category	binding
compartment	[Compartment:5263265] lumenal side of endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10264275
displayName	Binding of newly synthesized MHC class I heavy chain (HC) with calnexin
eventOf	[Pathway:R-CFA-983170] Antigen Presentation: Folding, assembly and peptide loading of class I MHC - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-983145] Binding of newly synthesized MHC class I heavy chain (HC) with calnexin - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-983091] CANX [lumenal side of endoplasmic reticulum membrane] [Complex:R-CFA-983120] monoglucosylated MHC class I HC [lumenal side of endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Binding of newly synthesized MHC class I heavy chain (HC) with calnexin
output	[Complex:R-CFA-983116] monoglucosylated MHC class I HC:Calnexin/BiP [lumenal side of endoplasmic reticulum membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-983145
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-983170] Antigen Presentation: Folding, assembly and peptide loading of class I MHC
(inferredTo)	[Reaction:R-HSA-983145] Binding of newly synthesized MHC class I heavy chain (HC) with calnexin

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