Reactome | ST6GALNAC2 transfers sialic acid to Core 1 mucins

Schema > Reaction > Entries

ST6GALNAC2 transfers sialic acid to Core 1 mucins Show undefined attributes

catalystActivity	[CatalystActivity:10263493] sialyltransferase activity of ST6GALNAC2 [Golgi membrane]
category	transition
compartment	[Compartment:17963] Golgi lumen [Compartment:20699] Golgi membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10263495
displayName	ST6GALNAC2 transfers sialic acid to Core 1 mucins
eventOf	[Pathway:R-CFA-977068] Termination of O-glycan biosynthesis - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-981814] ST6GALNAC2 transfers sialic acid to Core 1 mucins - Homo sapiens
input	[SimpleEntity:R-ALL-727815] CMP-Neu5Ac [Golgi lumen] [DefinedSet:R-CFA-1462240] Core 1 mucins [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	ST6GALNAC2 transfers sialic acid to Core 1 mucins GalNAc alpha-2,6-sialyltransferase II can add a sialic acid to the T antigen at the alpha 6 position
output	[SimpleEntity:R-ALL-727810] CMP [Golgi lumen] [SimpleEntity:R-ALL-425969] H+ [Golgi lumen] [DefinedSet:R-CFA-1463568] Sialyl-2,6 T antigens [Golgi lumen]
precedingEvent	[Reaction:R-CFA-1964505] C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-981814
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-977068] Termination of O-glycan biosynthesis
(inferredTo)	[Reaction:R-HSA-981814] ST6GALNAC2 transfers sialic acid to Core 1 mucins

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