Reactome | Complement factor I binds C4BP

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Complement factor I binds C4BP Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10263407
displayName	Complement factor I binds C4BP
eventOf	[Pathway:R-CFA-977606] Regulation of Complement cascade - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-981637] Complement factor I inactivates C4BP-bound C4b - Canis familiaris
inferredFrom	[Reaction:R-HSA-981658] Complement factor I binds C4BP - Homo sapiens
input	[Complex:R-CFA-981642] C4-binding protein:C4b [plasma membrane] [Complex:R-CFA-976749] CFI [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Complement factor I binds C4BP
output	[Complex:R-CFA-981633] C4b-binding protein:Factor I [plasma membrane]
precedingEvent	[Reaction:R-CFA-977626] C4b-binding protein binds C4b - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-981658
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-977606] Regulation of Complement cascade
(precedingEvent)	[Reaction:R-CFA-981637] Complement factor I inactivates C4BP-bound C4b
(inferredTo)	[Reaction:R-HSA-981658] Complement factor I binds C4BP

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