Reactome | Factor H displaces Bb

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Factor H displaces Bb Show undefined attributes

category	dissociation
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10263283
displayName	Factor H displaces Bb
eventOf	[Pathway:R-CFA-977606] Regulation of Complement cascade - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-977605] Factor H displaces Bb - Homo sapiens
input	[Complex:R-CFA-977373] Cell surface:CFH, CFHR3:C3bBb [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Factor H displaces Bb
output	[Complex:R-CFA-977596] Cell surface:FH,FHR3:C3b [plasma membrane] [EntityWithAccessionedSequence:R-CFA-182453] CFB [extracellular region]
precedingEvent	[Reaction:R-CFA-977363] Factor H binds to C3bBb - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-977605
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-977606] Regulation of Complement cascade
(inferredTo)	[Reaction:R-HSA-977605] Factor H displaces Bb