Reactome | PSPH:Mg2+ dimer dephosphorylates O-P-Ser

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PSPH:Mg2+ dimer dephosphorylates O-P-Ser Show undefined attributes

catalystActivity	[CatalystActivity:10263186] L-phosphoserine phosphatase activity of PSPH:Mg2+ dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10263188
displayName	PSPH:Mg2+ dimer dephosphorylates O-P-Ser
eventOf	[Pathway:R-CFA-977347] Serine metabolism - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-9014766] PXLP-K56-SRR dimer isomerises L-Ser to D-Ser - Canis familiaris [Reaction:R-CFA-8932980] SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane - Canis familiaris [Reaction:R-CFA-9929460] SDS dimers:PXLP convert L-Ser to PYR and NH4+ - Canis familiaris [Reaction:R-CFA-9034539] PXLP-K56-SRR dimer deaminates L-Ser - Canis familiaris
inferredFrom	[Reaction:R-HSA-977324] PSPH:Mg2+ dimer dephosphorylates O-P-Ser - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-936706] O-P-Ser [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PSPH:Mg2+ dimer dephosphorylates O-P-Ser H2O + O-phospho-L-serine => L-serine + phosphate phosphoserine is dephosphorylated
output	[SimpleEntity:R-ALL-200736] L-Ser [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-CFA-977333] PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-977324
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-977347] Serine metabolism
(precedingEvent)	[Reaction:R-CFA-9034539] PXLP-K56-SRR dimer deaminates L-Ser [Reaction:R-CFA-9014766] PXLP-K56-SRR dimer isomerises L-Ser to D-Ser [Reaction:R-CFA-8932980] SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane [Reaction:R-CFA-9929460] SDS dimers:PXLP convert L-Ser to PYR and NH4+
(inferredTo)	[Reaction:R-HSA-977324] PSPH:Mg2+ dimer dephosphorylates O-P-Ser

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