Reactome | Regulation of CDH1 posttranslational processing and trafficking to plasma membrane

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Regulation of CDH1 posttranslational processing and trafficking to plasma membrane Show undefined attributes

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10331919
displayName	Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
eventOf	[Pathway:R-CFA-9764265] Regulation of CDH1 Expression and Function - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[BlackBoxEvent:R-CFA-9932162] Removal of CDH1 signal peptide - Canis familiaris [BlackBoxEvent:R-CFA-9816276] CDH1 is N-glycosylated on asparagine residues in endoplasmic reticulum - Canis familiaris [BlackBoxEvent:R-CFA-9932344] MOGS removes terminal glucose from Glu3Man9GlcNAc2-CDH1 - Canis familiaris [BlackBoxEvent:R-CFA-9932352] Glucosidase II removes glucose residue from Glu2Man9GlucNAc2-CDH1 - Canis familiaris [BlackBoxEvent:R-CFA-9932988] CANX binds Glu1Man9GlcNAc2-CDH1 - Canis familiaris [BlackBoxEvent:R-CFA-9932913] Glucosidase II removes glucose residue from Glu1Man9GlucNAc2-CDH1 - Canis familiaris [BlackBoxEvent:R-CFA-9816277] CDH1 is O-manosylated - Canis familiaris [Reaction:R-CFA-9933380] Cytosolic tail of CDH1 is phosphorylated - Canis familiaris [Reaction:R-CFA-9933194] CTNNB1, JUP bind CDH1 - Canis familiaris [BlackBoxEvent:R-CFA-9816273] CDH1 translocates from ER to Golgi - Canis familiaris [Reaction:R-CFA-9816275] CDH1 is proteolytically cleaved in Golgi - Canis familiaris [Reaction:R-CFA-9935209] CDH1 binds to PIP5K1C - Canis familiaris [BlackBoxEvent:R-CFA-9816278] CDH1 translocates to the plasma membrane - Canis familiaris
inferredFrom	[Pathway:R-HSA-9768727] Regulation of CDH1 posttranslational processing and trafficking to plasma membrane - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Regulation of CDH1 posttranslational processing and trafficking to plasma membrane
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-9768727
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9764265] Regulation of CDH1 Expression and Function
(inferredTo)	[Pathway:R-HSA-9768727] Regulation of CDH1 posttranslational processing and trafficking to plasma membrane

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