Reactome | LRP2 binds extracellular TCN2:RCbl

Schema > Reaction > Entries

LRP2 binds extracellular TCN2:RCbl Show undefined attributes

catalystActivity	[CatalystActivity:10322362] cargo receptor activity of LRP2:LDLRAP1 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10322364
displayName	LRP2 binds extracellular TCN2:RCbl
eventOf	[Pathway:R-CFA-9758890] Transport of RCbl within the body - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-CFA-9759202] LRP2-mediated TCN2:RCbl uptake and delivery to lysosome - Canis familiaris
inferredFrom	[Reaction:R-HSA-9759209] LRP2 binds extracellular TCN2:RCbl - Homo sapiens
input	[Complex:R-CFA-9759635] LRP2:LDLRAP1 [plasma membrane] [Complex:R-CFA-9759429] TCN2:RCbl [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	LRP2 binds extracellular TCN2:RCbl
output	[Complex:R-CFA-9759208] LRP2:LDLRAP1:TCN2:RCbl [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9759209
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9758890] Transport of RCbl within the body
(precedingEvent)	[BlackBoxEvent:R-CFA-9759202] LRP2-mediated TCN2:RCbl uptake and delivery to lysosome
(inferredTo)	[Reaction:R-HSA-9759209] LRP2 binds extracellular TCN2:RCbl

Cite Us!