Reactome | ESR1 binds ESR1 agonists

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10321663
displayName	ESR1 binds ESR1 agonists
eventOf	[Pathway:R-CFA-8939211] ESR-mediated signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9716947] ESR1 binds ESR1 agonists - Homo sapiens
input	[DefinedSet:R-ALL-9716925] ESR1 agonists [nucleoplasm] [Complex:R-CFA-8939185] ESR1:chaperone complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	ESR1 binds ESR1 agonists
output	[Complex:R-CFA-9716887] ESR1:ESR1 agonists [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9716947
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-8939211] ESR-mediated signaling
(inferredTo)	[Reaction:R-HSA-9716947] ESR1 binds ESR1 agonists

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