Reactome | PDE4A binds PDE4A inhibitors

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10321047
displayName	PDE4A binds PDE4A inhibitors
eventOf	[Pathway:R-CFA-418555] G alpha (s) signalling events - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9708275] PDE4A binds PDE4A inhibitors - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-52383] PDE4A [cytosol] [CandidateSet:R-ALL-9708276] PDE4A inhibitors [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PDE4A binds PDE4A inhibitors
output	[Complex:R-CFA-9708248] PDE4A:PDE4A inhibitors [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9708275
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-418555] G alpha (s) signalling events
(inferredTo)	[Reaction:R-HSA-9708275] PDE4A binds PDE4A inhibitors

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