Reactome | ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG

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ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG Show undefined attributes

catalystActivity	[CatalystActivity:10318185] beta-galactoside (CMP) alpha-2,3-sialyltransferase activity of ST3GAL3 [Golgi membrane]
category	transition
compartment	[Compartment:17963] Golgi lumen [Compartment:20699] Golgi membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10318187
displayName	ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG
eventOf	[Pathway:R-CFA-9037629] Lewis blood group biosynthesis - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-9605609] FUT3 transfers Fuc to Type 1 MSGG to form sLeA - Canis familiaris [Reaction:R-CFA-9603991] ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG - Canis familiaris
inferredFrom	[Reaction:R-HSA-9603987] ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG - Homo sapiens
input	[SimpleEntity:R-ALL-727815] CMP-Neu5Ac [Golgi lumen] [SimpleEntity:R-ALL-9036984] Type 1 chain [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG
output	[SimpleEntity:R-ALL-727810] CMP [Golgi lumen] [SimpleEntity:R-ALL-9605595] Type 1 MSGG [Golgi lumen]
precedingEvent	[Reaction:R-CFA-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9603987
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9037629] Lewis blood group biosynthesis
(precedingEvent)	[Reaction:R-CFA-9605609] FUT3 transfers Fuc to Type 1 MSGG to form sLeA [Reaction:R-CFA-9603991] ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG
(inferredTo)	[Reaction:R-HSA-9603987] ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG

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