Reactome | FUT3 transfers Fuc to Type 1 chains to form LeA

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FUT3 transfers Fuc to Type 1 chains to form LeA Show undefined attributes

catalystActivity	[CatalystActivity:10296744] 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity of FUT3 [Golgi membrane]
category	transition
compartment	[Compartment:17963] Golgi lumen [Compartment:20699] Golgi membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10318184
displayName	FUT3 transfers Fuc to Type 1 chains to form LeA
eventOf	[Pathway:R-CFA-9037629] Lewis blood group biosynthesis - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9603986] FUT3 transfers Fuc to Type 1 chains to form LeA - Homo sapiens
input	[SimpleEntity:R-ALL-205683] GDP-Fuc [Golgi lumen] [SimpleEntity:R-ALL-9036984] Type 1 chain [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	FUT3 transfers Fuc to Type 1 chains to form LeA
output	[SimpleEntity:R-ALL-205689] GDP [Golgi lumen] [SimpleEntity:R-ALL-9605607] LeA [Golgi lumen]
precedingEvent	[Reaction:R-CFA-9603989] B3GALTs transfer Gal to GlcNAc-?1,3-Gal-R to form Type 1 chain - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9603986
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-9037629] Lewis blood group biosynthesis
(inferredTo)	[Reaction:R-HSA-9603986] FUT3 transfers Fuc to Type 1 chains to form LeA

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