Reactome | GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-CFA-913413] High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] - Canis familiaris [Complex:R-CFA-913413] High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane] - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10260922
displayName	GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane]
hasComponent	[Complex:R-CFA-913362] GM-CSF:GM-CSF receptor alpha subunit [plasma membrane] [Complex:R-CFA-879945] IL3RB:JAK2 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-913389] GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane] - Homo sapiens
maxDepth	3
memberOf	[DefinedSet:R-CFA-913364] High affinity binding complexes of interleukin receptors using the Common beta chain [plasma membrane] - Canis familiaris
name	GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2
producedByEvent	[Reaction:R-CFA-913371] GM-CSF receptor alpha:GM-CSF binds Bc - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-913389
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasMember)	[DefinedSet:R-CFA-913364] High affinity binding complexes of interleukin receptors using the Common beta chain [plasma membrane] [DefinedSet:R-CFA-904816] Tyrosine kinases that phosphorylate the Common beta chain [plasma membrane]
(output)	[Reaction:R-CFA-913371] GM-CSF receptor alpha:GM-CSF binds Bc
(hasComponent)	[Complex:R-CFA-913413] High affinity GM-CSF receptor complex dimer, inactive JAK2 [plasma membrane]
(inferredTo)	[Complex:R-HSA-913389] GM-CSF:GM-CSF receptor alpha subunit:Common beta chain:JAK2 [plasma membrane]

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