Reactome | Activated NTRK2 signals through PLCG1

Schema > Pathway > Entries

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10331731
displayName	Activated NTRK2 signals through PLCG1
eventOf	[Pathway:R-CFA-9006115] Signaling by NTRK2 (TRKB) - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:182] neurotrophin TRK receptor signaling pathway
hasDiagram	false
hasEHLD	false
hasEvent	[BlackBoxEvent:R-CFA-9026894] Activated PCLG1 dissociates from NTRK2 - Canis familiaris
inferredFrom	[Pathway:R-HSA-9026527] Activated NTRK2 signals through PLCG1 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Activated NTRK2 signals through PLCG1
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-9026527
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-9006115] Signaling by NTRK2 (TRKB)
(inferredTo)	[Pathway:R-HSA-9026527] Activated NTRK2 signals through PLCG1

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