Reactome | IL34 binds CSF1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10316231
displayName	IL34 binds CSF1
eventOf	[Pathway:R-CFA-449836] Other interleukin signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-CFA-9009485] IL34:CSF1 binds CSF1R - Canis familiaris
inferredFrom	[Reaction:R-HSA-9009488] IL34 binds CSF1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-9009484] CSF1 [extracellular region] [EntityWithAccessionedSequence:R-CFA-448636] IL34 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	IL34 binds CSF1
output	[Complex:R-CFA-9009490] IL34:CSF1 [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-9009488
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-449836] Other interleukin signaling
(precedingEvent)	[BlackBoxEvent:R-CFA-9009485] IL34:CSF1 binds CSF1R
(inferredTo)	[Reaction:R-HSA-9009488] IL34 binds CSF1