Reactome | IL35:(IL12RB2:p-JAK2) dimer [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-CFA-8983877] IL35:(IL12RB2:p-JAK2) dimer:p-STAT4 [plasma membrane] - Canis familiaris
consumedByEvent	[BlackBoxEvent:R-CFA-8983876] STAT4 binds IL12RB2:IL12RB2 - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10315581
displayName	IL35:(IL12RB2:p-JAK2) dimer [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-CFA-447249] IL12RB2 [plasma membrane] 2 × [Complex:R-CFA-622267] IL35 [extracellular region] 2 × [EntityWithAccessionedSequence:R-CFA-210621] phospho-p-JAK2 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8983873] IL35:(IL12RB2:p-JAK2) dimer [plasma membrane] - Homo sapiens
maxDepth	3
name	IL35:(IL12RB2:p-JAK2) dimer
producedByEvent	[BlackBoxEvent:R-CFA-8983878] p-STAT4 dissociates from IL12RB2:IL12RB2 receptor - Canis familiaris [BlackBoxEvent:R-CFA-8983870] JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-8983873
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-CFA-8983878] p-STAT4 dissociates from IL12RB2:IL12RB2 receptor [BlackBoxEvent:R-CFA-8983870] JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated
(input)	[BlackBoxEvent:R-CFA-8983876] STAT4 binds IL12RB2:IL12RB2
(hasComponent)	[Complex:R-CFA-8983877] IL35:(IL12RB2:p-JAK2) dimer:p-STAT4 [plasma membrane] [Complex:R-CFA-8983881] IL35:(IL12RB2:p-JAK2) dimer:STAT4 [plasma membrane]
(inferredTo)	[Complex:R-HSA-8983873] IL35:(IL12RB2:p-JAK2) dimer [plasma membrane]