Reactome | RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA

Schema > Reaction > Entries

RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA Show undefined attributes

catalystActivity	[CatalystActivity:10314926] 3-hydroxyacyl-CoA dehydratase activity of HTD2 [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10314928
displayName	RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA
eventOf	[Pathway:R-CFA-75105] Fatty acyl-CoA biosynthesis - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8957389] RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-8957387] 3HA-CoA [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA a (3R)-3-hydroxyacyl-CoA => a (2E)-enoyl-CoA + H2O
output	[SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix] [SimpleEntity:R-ALL-8957386] t2E-CoA [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8957389
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-75105] Fatty acyl-CoA biosynthesis
(inferredTo)	[Reaction:R-HSA-8957389] RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA

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