Reactome | RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-CFA-8956077] RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-8956103] VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10314848
displayName	RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol]
hasComponent	[Complex:R-CFA-8955646] COMMDs:CCDC22 [cytosol] [EntityWithAccessionedSequence:R-CFA-8952511] CUL2 [cytosol] [CandidateSet:R-CFA-8952547] DCUN1D1,2,4,5 [cytosol] [EntityWithAccessionedSequence:R-CFA-180582] RBX1 [cytosol] [Complex:R-CFA-390483] VBC complex [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8956074] RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] - Homo sapiens
maxDepth	4
name	RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5
producedByEvent	[BlackBoxEvent:R-CFA-9755303] 26S proteasome degrades HIFalpha - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-8956074
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-CFA-9755303] 26S proteasome degrades HIFalpha
(input)	[Reaction:R-CFA-8956103] VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha
(hasComponent)	[Complex:R-CFA-8956077] RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] [Complex:R-CFA-8956079] ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] [Complex:R-CFA-8956082] RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol]
(inferredTo)	[Complex:R-HSA-8956074] RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol]

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