Reactome | hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10313051
displayName	hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb
eventOf	[Pathway:R-CFA-9020702] Interleukin-1 signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8948015] hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb - Homo sapiens
input	[Complex:R-CFA-450159] hp-IRAK1:3xTRAF6 [cytosol] 3 × [Complex:R-CFA-8948017] UBE2N:UBE2V1:K63polyUb [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb
output	[Complex:R-CFA-8948014] hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8948015
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-9020702] Interleukin-1 signaling
(inferredTo)	[Reaction:R-HSA-8948015] hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb

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