Reactome | RUNX1 binds PAX5 (BSAP)

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10311948
displayName	RUNX1 binds PAX5 (BSAP)
eventOf	[Pathway:R-CFA-8939245] RUNX1 regulates transcription of genes involved in BCR signaling - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8938951] RUNX1 binds PAX5 (BSAP) - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-158583] PAX5 [nucleoplasm] [Complex:R-CFA-8865330] RUNX1:CBFB [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	RUNX1 binds PAX5 (BSAP)
output	[Complex:R-CFA-8938948] RUNX1:CBFB:PAX5 [nucleoplasm]
precedingEvent	[Reaction:R-CFA-8865320] CBFB binds RUNX1 - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8938951
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-8939245] RUNX1 regulates transcription of genes involved in BCR signaling
(inferredTo)	[Reaction:R-HSA-8938951] RUNX1 binds PAX5 (BSAP)

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