Reactome | Aryl hydrocarbon receptor signalling

Schema > Pathway > Entries

created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10331577
displayName	Aryl hydrocarbon receptor signalling
eventOf	[Pathway:R-CFA-211945] Phase I - Functionalization of compounds - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:8764] xenobiotic metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-CFA-8937177] AHR:TCDD binds ARNT - Canis familiaris [Reaction:R-CFA-8936851] AHRR binds ARNT - Canis familiaris
inferredFrom	[Pathway:R-HSA-8937144] Aryl hydrocarbon receptor signalling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Aryl hydrocarbon receptor signalling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49646] Canis familiaris
stId	R-CFA-8937144
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEncapsulatedEvent)	[Pathway:R-CFA-400206] Regulation of lipid metabolism by PPARalpha
(hasEvent)	[Pathway:R-CFA-211945] Phase I - Functionalization of compounds
(inferredTo)	[Pathway:R-HSA-8937144] Aryl hydrocarbon receptor signalling

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