Reactome | GUCY2C trimer binds GUCA2A,B

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10311617
displayName	GUCY2C trimer binds GUCA2A,B
eventOf	[Pathway:R-CFA-8935690] Digestion - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8936214] GUCY2C trimer binds GUCA2A,B - Homo sapiens
input	[DefinedSet:R-CFA-8936209] GUCA2A,B [extracellular region] [Complex:R-CFA-8936213] GUCY2C trimer [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	GUCY2C trimer binds GUCA2A,B
output	[Complex:R-CFA-8936204] GUCY2C trimer:GUCA2A,B [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8936214
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-8935690] Digestion
(inferredTo)	[Reaction:R-HSA-8936214] GUCY2C trimer binds GUCA2A,B

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