Reactome | p-Y389,400-RUFY1 binds PI3P

Schema > Reaction > Entries

p-Y389,400-RUFY1 binds PI3P Show undefined attributes

catalystActivity	[CatalystActivity:10310293] protein-macromolecule adaptor activity of p-Y389,400-RUFY1 [early endosome membrane]
category	transition
compartment	[Compartment:171062] early endosome membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10310295
displayName	p-Y389,400-RUFY1 binds PI3P
eventOf	[Pathway:R-CFA-1660499] Synthesis of PIPs at the plasma membrane - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8871376] p-Y389,400-RUFY1 binds PI3P - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-5215951] phospho-RUFY1 [early endosome membrane] [SimpleEntity:R-ALL-1806200] PI3P [early endosome membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	p-Y389,400-RUFY1 binds PI3P
output	[Complex:R-CFA-8871354] p-Y389,400-RUFY1:PI3P [early endosome membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8871376
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-1660499] Synthesis of PIPs at the plasma membrane
(inferredTo)	[Reaction:R-HSA-8871376] p-Y389,400-RUFY1 binds PI3P