Reactome | SNX9 recruits components of the actin polymerizing machinery

Schema > Reaction > Entries

SNX9 recruits components of the actin polymerizing machinery Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10309574
displayName	SNX9 recruits components of the actin polymerizing machinery
eventOf	[Pathway:R-CFA-8856828] Clathrin-mediated endocytosis - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-8868236] BAR domain proteins recruit dynamin - Canis familiaris
inferredFrom	[Reaction:R-HSA-8868230] SNX9 recruits components of the actin polymerizing machinery - Homo sapiens
input	[Complex:R-CFA-8868713] ARP2/3 complex [cytosol] [Polymer:R-CFA-202986] f-actin [plasma membrane] [Complex:R-CFA-8868219] HIP1 dimer [cytosol] [Complex:R-CFA-8868221] HIP1R dimer [cytosol] [Complex:R-CFA-8867751] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] [EntityWithAccessionedSequence:R-CFA-201873] WASL [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SNX9 recruits components of the actin polymerizing machinery
output	[Complex:R-CFA-8868232] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane]
precedingEvent	[Reaction:R-CFA-8867754] F- and N- BAR domain proteins bind the clathrin-coated pit - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8868230
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-8856828] Clathrin-mediated endocytosis
(precedingEvent)	[Reaction:R-CFA-8868236] BAR domain proteins recruit dynamin
(inferredTo)	[Reaction:R-HSA-8868230] SNX9 recruits components of the actin polymerizing machinery