Reactome | PP2A demethylation by PPME1

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PP2A demethylation by PPME1 Show undefined attributes

catalystActivity	[CatalystActivity:10308259] protein methylesterase activity of PPME1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10308261
displayName	PP2A demethylation by PPME1
eventOf	[Pathway:R-CFA-69273] Cyclin A/B1/B2 associated events during G2/M transition - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8856951] PP2A demethylation by PPME1 - Homo sapiens
input	[SimpleEntity:R-ALL-113518] H2O [nucleoplasm] [Complex:R-CFA-8857787] MeL-PP2A [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PP2A demethylation by PPME1
output	[SimpleEntity:R-ALL-8857797] methanol [nucleoplasm] [Complex:R-CFA-1363265] PP2A [nucleoplasm]
precedingEvent	[Reaction:R-CFA-8856945] PP2A methylation by LCMT1 - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8856951
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-69273] Cyclin A/B1/B2 associated events during G2/M transition
(inferredTo)	[Reaction:R-HSA-8856951] PP2A demethylation by PPME1

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