Reactome | Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates

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Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates Show undefined attributes

category	dissociation
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10307463
displayName	Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates
eventOf	[Pathway:R-CFA-977606] Regulation of Complement cascade - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8852481] Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates - Homo sapiens
input	[Complex:R-CFA-8959915] Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates
output	2 × [Complex:R-CFA-8959919] Activated C1R:SERPING1 [extracellular region] 2 × [Complex:R-CFA-8959917] Activated C1S:SERPING1 [extracellular region] [Complex:R-CFA-173552] Antigen:IgG [plasma membrane] [Complex:R-CFA-173579] C1Q [extracellular region]
precedingEvent	[Reaction:R-CFA-9021306] C1-Inh binds and inactivates C1r, C1s - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8852481
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-977606] Regulation of Complement cascade
(inferredTo)	[Reaction:R-HSA-8852481] Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates

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