Reactome | GTSE1 binds PLK1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10307439
displayName	GTSE1 binds PLK1
eventOf	[Pathway:R-CFA-8852276] The role of GTSE1 in G2/M progression after G2 checkpoint - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CFA-8852317] PLK1 phosphorylates GTSE1 - Canis familiaris
inferredFrom	[Reaction:R-HSA-8852324] GTSE1 binds PLK1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-CFA-8852264] GTSE1 [cytosol] [EntityWithAccessionedSequence:R-CFA-3000318] phospho-PLK1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GTSE1 binds PLK1
output	[Complex:R-CFA-8852323] GTSE1:p-T210-PLK1 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-8852324
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CFA-8852276] The role of GTSE1 in G2/M progression after G2 checkpoint
(precedingEvent)	[Reaction:R-CFA-8852317] PLK1 phosphorylates GTSE1
(inferredTo)	[Reaction:R-HSA-8852324] GTSE1 binds PLK1