Reactome | Cap Binding Complex (CBC) [nucleoplasm]

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Cap Binding Complex (CBC) [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-CFA-9970291] capped, methylated pre-mRNA:CBC Complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] - Canis familiaris [Complex:R-CFA-6814907] CBCAP:capped pre-snRNA [nucleoplasm] - Canis familiaris [Complex:R-CFA-113715] RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-77095] Recognition and binding of the mRNA cap by the cap-binding complex - Canis familiaris [Reaction:R-CFA-6814885] CBCAP complex binds 7-methylguanosine cap of snRNA - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10229041
displayName	Cap Binding Complex (CBC) [nucleoplasm]
hasComponent	[EntityWithAccessionedSequence:R-CFA-51469] NCBP1 [nucleoplasm] [EntityWithAccessionedSequence:R-CFA-51463] NCBP2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-77088] Cap Binding Complex (CBC) [nucleoplasm] - Homo sapiens
maxDepth	2
name	Cap Binding Complex (CBC)
producedByEvent	[Reaction:R-CFA-77594] Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC - Canis familiaris [Reaction:R-CFA-111439] Docking of Mature Histone mRNA complex:TAP at the NPC - Canis familiaris [Reaction:R-CFA-77094] Formation of cap binding complex (CBC) - Canis familiaris [Reaction:R-CFA-112381] Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-77088
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(hasComponent)	[Complex:R-CFA-9970291] capped, methylated pre-mRNA:CBC Complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] [Complex:R-CFA-9970403] capped, methylated pre-mRNA:CBC Complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] [Complex:R-CFA-9970292] capped, methylated pre-mRNA:CBC Complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] [Complex:R-CFA-9970391] capped, methylated pre-mRNA:CBC Complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] [Complex:R-CFA-9970256] capped, methylated pre-mRNA:CBC Complex (RNA Pol II dephosphorylated on Ser5) [nucleoplasm] [Complex:R-CFA-9970288] capped, methylated pre-mRNA:CBC Complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] [Complex:R-CFA-9970325] capped, methylated pre-mRNA:CBC Complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] [Complex:R-CFA-6814903] CBCAP:capped snRNA U1,U2,U4,U4atac,U5,U11,U12 [nucleoplasm] [Complex:R-CFA-6814907] CBCAP:capped pre-snRNA [nucleoplasm] [Complex:R-CFA-113715] RNA Pol II (hypophosphorylated):capped pre-mRNA complex [nucleoplasm] [Complex:R-CFA-112167] Mature intronless derived mRNA complex [nucleoplasm] [Complex:R-CFA-9970411] capped, methylated, polyadenylated pre-mRNA:CBC Complex [nucleoplasm] [Complex:R-CFA-71954] capped, methylated pre-mRNA:CBC Complex [nucleoplasm] [Complex:R-CFA-9770418] mRNA 5' exon:CBC complex [nucleoplasm] [Complex:R-CFA-9770431] spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] [Complex:R-CFA-8850671] Spliced mRNA:CBC:EJC:TREX [nucleoplasm] [Complex:R-CFA-72157] Spliced mRNP [nucleoplasm] [Complex:R-CFA-8849126] capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] [Complex:R-CFA-113815] NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] [Complex:R-CFA-77089] capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex [nucleoplasm] [Complex:R-CFA-110758] Capped Intronless Histone pre-mRNA:CBC complex [nucleoplasm] [Complex:R-CFA-156959] Mature intronless transcript derived Histone pre-mRNA:CBC complex [nucleoplasm] [Complex:R-CFA-6803524] capped, methylated pre-FGFR2 mRNA:CBC complex [nucleoplasm] [Complex:R-CFA-191887] m7G capped snRNA:CBC:PHAX complex [nucleoplasm]
(input)	[Reaction:R-CFA-6814885] CBCAP complex binds 7-methylguanosine cap of snRNA [Reaction:R-CFA-77095] Recognition and binding of the mRNA cap by the cap-binding complex
(output)	[Reaction:R-CFA-112381] Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex [Reaction:R-CFA-77594] Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC [Reaction:R-CFA-111439] Docking of Mature Histone mRNA complex:TAP at the NPC [Reaction:R-CFA-77094] Formation of cap binding complex (CBC)
(inferredTo)	[Complex:R-HSA-77088] Cap Binding Complex (CBC) [nucleoplasm]

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